Gut Health Test
Microbiomes
The following are all potential signs of sub-optimal gut health:
- Bloating
- Diarrhea
- Abdominal pain or discomfort
- Gas
- Constipation
- Fatigue
- Weight fluctuations
- Skin issues- allergy, acne
- Mood disorders
- immune system disorders (e.g. allergy – both inhalative and nutritive, increased susceptibility to infection)
- after the completion of antibiotic therapy
- Sleep disturbance, insomnia
- in case of lethargy, fatigue
- in case of food intolerance
- to assess the effect of eating habits and diets
Food Intolerance Test
On exposure to certain foods, your immune system can react by releasing proteins called antibodies. Foods that cause antibodies to be released are called antigens or allergens. Two types of antibodies are commonly produced in response to foods: IgE (immunoglobulin E) and IgG (immunoglobulin G). A food allergy is an immediate reaction caused by the production of IgE antibodies, while a food sensitivity is a delayed reaction caused by the production of IgG antibodies to specific foods.The IgG Food Sensitivity test measures levels of IgG antibodies to over 220 different foods. Antibodies are highly specialized proteins that bind to specific antigens. All foods have antigen molecules on them, and sometimes these food antigens can trigger the production of antibodies. Two types of food sensitivity tests panels are available.
1. Food IgG 222: measure IgG antibodies to 222 food antigens 2. Food inflammatory test 134 and 44: measure IgG antibodies and complementary reaction to food antigens that cause inflammation in body to 134 or 44 food antigens
You can develop a food sensitivity at any age. Because IgG food reactions take hours or days to develop, this makes it difficult to determine which food is responsible for the reaction without doing testing. You should speak with your healthcare provider if you have the following on going symptoms:
Systemic: Fever, fatigue, chills, sweating and feeling weak, puffiness.
Skin: Itching, redness, swelling, and rashes.
Brain: Mood and memory disturbances, behavioural problems.
Lungs: Food-induced bronchitis and asthma symptoms.
Musculoskeletal: Joint pain, muscle stiffness and swelling.
Digestive tract: Nausea & vomiting, diarrhea, abdominal pain, gas, and bloating
Quad Test
Colorectal cancer is the second leading cause of illness and death in the Western world. The screening using fecal occult blood tests is based on the bleeding detection, as important symptom of colonic neoplasm, either at an early-stage cancer or large adenomatous polyps. Colorectal cancer is also associated with local acute inflammatory reaction being visualized, in some cases, by white cell neutrophil scanning. Quad test is CerTest FOB+Transferrin+Calprotectin+Lactoferrin combo test offers a simple, highly sensitive and non-invasive screening assay to make a presumptive diagnosis of gastrointestinal bleeding and inflammatory disorder caused by colorectal cancer.
Haemoglobin (CerTest FOB) is the iron-containing oxygen-transport protein in the red blood cells that may be leaked into gastrointestinal tract and then discharged with the faeces in gastrointestinal bleeding diseases. Transferrin is a blood-derived component that may be leaked into gastrointestinal tract and then discharged with the faeces in gastrointestinal bleeding diseases. Transferrin is stable in faeces and a good marker to detect loss of blood from the upper and lower intestine (gastrointestinal bleeding). Calprotectin is a neutrophil cytosolic protein with antimicrobial properties, which is present at increased concentration in stool during bowel inflammation. Calprotectin inhibits zinc-dependent enzyme systems, killing microbes and inducing apoptosis in normal and cancer cells. Lactoferrin is a glycoprotein component of neutrophil secondary granules, a primary component of the acute inflammatory response released from fecal leukocytes. This protein is resistant to proteolysis in the faeces and may serve as a marker of inflammation in the intestine. The major cause of fecal neutrophils in patients with chronic diarrhea is chronic inflammatory bowel disease of the colon (i.e., Crohn’s disease and ulcerative colitis).
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UNDER CONSTRUCTION
The Intestinal Permeability Test
The Intestinal Permeability test, sometimes known as the leaky gut test, assesses damage to the lining of the gastrointestinal tract.
Changes in intestinal permeability are associated with many health conditions, including autism, autoimmune disorders, food sensitivities and inflammatory bowel disease. This ‘leaky gut’ causes disease because the perturbed intestinal barrier allows toxic molecules to enter the bloodstream and poison the body. Intestinal permeability can be measured using this test.
The intestinal permeability test, which assesses lactulose and mannitol recovery can be used to monitor improvements or deterioration in intestinal permeability as a result of therapy, disease or drug use. Furthermore, the leaky gut test has been used to monitor the compliance and effectiveness of a gluten-free diet in patients with Coeliac disease.The test works on the principle that small molecules (i.e. mannitol) are readily absorbed by the intestinal villi, whilst larger molecules such as disaccharides (i.e. lactulose) are not.
These water soluble non-metabolised sugar molecules after penetrating the intestinal tract are excreted into the urine. Under normal circumstances the ratio of lactulose to mannitol in urine is low (i.e lactulose is not absorbed), mannitol is absorbed. When the structure of the intestinal epithelium is jeopardised (‘leaky gut’ is present), the large sugar molecule can permeate the mucosa and is recovered in the urine. In this situation, the level of lactulose is increased in the urine and therefore the ratio of lactulose to mannitol is high.
In addition to assessing leaky gut, this test can also help diagnose malabsorption. If a low level of mannitol which normally penetrates the intestinal epithelium is observed, it may indicate malabsorption of small molecules and possible atrophy of the intestinal villi.
